GHR HEK293
CBP74670
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| I. Background | |
| GHR（生长激素受体）是细胞因子受体超家族成员，介导生长激素（GH）的多种生理效应。GH与GHR结合后诱导受体二聚化，激活JAK2/STAT5等信号通路，调控骨骼生长、代谢和细胞增殖。其基因突变可导致Laron综合征（生长激素不敏感综合征），表现为严重矮小。 | |
| II. Description | |
| GHR HEK293细胞，在 HEK293细胞的基础上，稳定表达 GHR。 | |
| III. Introduction | |
| Expressed gene: | GHR |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant GHR HEK293 constitutively expressing GHR. |
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